Martin Christ Freeze Dryers

Better process control and repeatability for a safe and rapid freeze-drying, high-quality products

The company manufactures MARTIN CHRIST as the leading manufacturer with over 55 years experience not only first class equipment for standard applications, but also a finely graded series of equipment for product specific drying processes with wide-ranging possibilities for optimization, from lab to production. This series is distinguished by its innovative system control LSC (Lyo-Screen-Control), its outstanding design in detail and further improved refrigeration and vacuum technology. There are laboratory freeze dryer with a cylindrical drying chamber and pilot plants with a rectangular cross-section of the product space available. The diverse and practical range of accessories enables the modification of the appropriate basic equipment for the various tasks of the user.

Outstanding products through superior technology and comprehensive customer service

The implementation of advanced applications - with-quality product - at first ahead of overall use of appropriate plant configuration. We consult extensively before purchasing the system and, at the request of drying tests in our application laboratory.

The proverbial quality of CHRIST freeze dryers, we have associated with a modern, intuitive, sensitive user interface LSC. This unit control "Lyo-Screen-Control" is used consistently in the laboratory and pilot freeze dryers, and already allows for the smallest devices, the input of up to 30 drying programs ("recipes") and the connection of a PC for process documentation and / or process control.

Their range of tasks and the best equipment Process Monitoring

Increasingly, already required to freeze dryer for small batches knowledge-intensive requirements such as creating documents, validation (IQ / OQ documentation ") and the provision of monitoring tools to ensure proper quality in our applications laboratory. For this we use not only the widespread measurement of product temperature and pressure gradient (pressure rise test "one), but also the measurement of electrical resistance (" Lyo-Control ") and the weight of the sample (" load cell ") during the process. Thus, our systems guarantee optimum product protection. Illegal structural changes up to the collapse of the matrix or thawing of possible cross-contamination can be avoided with certainty.

The best system for advanced application

• Compact and powerful laboratory or pilot plant equipment with small footprint
• New asset management LSC with groundbreaking ease of use and PC-Interface for process monitoring and documentation
• Modular construction to expand capacity on a multiple basis of extensive range of accessories
• Plant design complies with FDA and cGMP guidelines, the system controller complies with the applicable requirements of GAMP, Lyo software LPC-16 also meets U.S. CFR
• Full implementation of the entire freeze drying process (freezing and drying) in the condenser chamber, program request, single-stage refrigeration for freezing at -25 ° C to -50 ° C (two-stage refrigeration)
• Ice condenser chamber with inner condenser coil for efficient vapor deposition, made entirely of stainless steel (W. no. 1.4571, "Pharma Steel)
• Equipment for freeze drying of solvents (eg DMSO, acetonitrile, Tertiärbuthanol, dioxane, ...) and Chemically available (Option)
• Ice condenser to control visual
• Ice condenser easily accessible, simple and quick defrosting and cleaning (option: Hot gas), electrical or gas defrosting
• Low power losses and no condensation through high-quality thermal insulation of the ice condenser chamber
• Drying chamber is located directly above the ice condenser, maximum cross-sectional area, high sublimation and reduced drying times
• All systems available with the Windows-based software LPC-16 ("Lyophilization Process Control) for PC-Prozesssteuerung/Dokumentation
• Alternatively, simple process documentation CHRIST printer or software "Lyo-Log"
• If desired, system qualification (IQ / OQ documentation ") for validation purposes

When selecting your freeze dryer next to the definition on the accessories and vessels used the following criteria are considered:

• The required ice condenser temperature (-55 ° C in aqueous samples, -85 ° C with solvent or low freezing samples)
• The required floor space or number of pistons to place the planned amount of product per drying cycle in or on the plant.
• The maximum ice (condensation capacity per 24 hours or the total capacity until defrosting).

Safe and gentle evaporation of solvents with a rotary vacuum concentrator (RVC)

A second, more than 20 years of structured business covers the development and production of rotational-vacuum-concentrators ("RVC"). Of particular advantage is the close relationship with our sister company Sigma laboratory centrifuges.

It is a well-graded series of RVC in combination with different cooling traps and vacuum pumps available, which is every application.

Examples for multiple applications:

• Efficient concentration of DNA / RNA, proteins etc.
• Genetic engineering and molecular biology
• Sample preparation in HPLC, GC, MS ...
• Natural insulation for durability
• Storage and handling of substances (compound libraries)
• Combinatorial chemistry
• High-throughput screening (HTS)
• General Eindampfaufgaben in the laboratory

bhbhb, Wednesday, April 7, 2010